Genetic variability of CYP3A4 in a heterogeneous Brazilian population from Maranhão
نویسندگان
چکیده
منابع مشابه
Genetic variability of CYP3A4 in a heterogeneous Brazilian population from Maranhão.
Inter-individual variability in drug metabolism may result in adverse drug responses. Pharmacogenetic studies have shown that polymorphisms in drug metabolizing enzymes may contribute to this variability. Among these enzymes, CYP3A4 is responsible for metabolizing over 50% of the clinically used drugs. The Brazilian population is composed of people with Native American, European, and African an...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2016
ISSN: 1676-5680
DOI: 10.4238/gmr.15017275